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KMID : 0370220030470050307
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Yakhak Hoeji
2003 Volume.47 No. 5 p.307 ~ p.310
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Hypouricemic Activity of Actinidia polygama
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강효주/Kang HJ
김유경/최진규/정성현/Kim UK/Choi JG/Chung SH
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Abstract
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Ethanol extract of Actinidia polygama Max. (AP) was examined for hypouricemic activity in potassium oxonate-induced hyperuricemic animal model. Ethanol extract of AP lo wered the plasma uric acid level by 20% when compared to the hyperuricemic control group. AP ether fraction at a dose of 100 mg/kg showed 27% reduction, whose efficacy was comparable to the probenecid-treated group. AP ether fraction-treated group also showed 23% reduction of urate in urine and this result suggests that AP ether fraction has anti-gout activity probably due to xanthine oxidase inhibition.
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KEYWORD
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